Monday, October 10, 2016

Murine Ear Drops otic


Generic Name: carbamide peroxide (otic) (KAR ba mide per OX ide OH tik)

Brand Names: Auraphene-B, Auro Ear Drops, Debrox, Ear Wax, Ear Wax Removal, Mollifene, Murine Ear Drops


What is carbamide peroxide?

Carbamide peroxide otic (for the ears) is used to soften and loosen ear wax, making it easier to remove.


Carbamide peroxide may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about carbamide peroxide?


You should not use this medication if you are allergic to carbamide peroxide, or if you have a ruptured ear drum. Do not use carbamide peroxide if you have any signs of ear infection or injury, such as pain or other irritation, or drainage, discharge, or bleeding from the ear. Do not use this medication in a child younger than 12 years old without the advice of a doctor.

You may hear a bubbling sound inside your ear after using carbamide peroxide ear drops. This is caused by the foaming action of carbamide peroxide, which helps break up the wax inside your ear.


Do not use carbamide peroxide for longer than 4 days in a row. Call your doctor if your ear symptoms do not improve after treatment, or if they get worse. Stop using carbamide peroxide and call your doctor at once if you have a serious side effect such as dizziness, ear pain or other irritation, decreased hearing for a prolonged period of time, or discharge or bleeding from the ear.

What should I discuss with my health care provider before using carbamide peroxide?


You should not use this medication if you are allergic to carbamide peroxide, or if you have any signs of ear infection or injury such as:

  • ear pain, itching, or other irritation;




  • drainage or discharge from the ear; or




  • bleeding from the ear.




FDA pregnancy category C. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Do not use this medication in a child younger than 12 years old without the advice of a doctor.

How should I use carbamide peroxide?


Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


The usual dose of this medication for children is 1 to 5 drops per ear twice daily. The usual dose for adults is 5 to 10 drops per ear twice daily. Follow your doctor's instructions. Carbamide peroxide may be used for up to 4 days, unless your doctor has told you otherwise.


To use the ear drops, first remove the cap from the dropper bottle. Lie down or tilt your head with your ear facing upward. Pull back on your ear gently to open up the ear canal. Hold the dropper upside down over your ear canal and drop the correct number of ear drops into the ear.


You may hear a bubbling sound inside your ear after putting in the drops. This is caused by the foaming action of carbamide peroxide, which helps break up the wax inside your ear.


After using the ear drops, stay lying down or with your head tilted for at least 5 minutes. You may use a small piece of cotton ball to plug the ear and keep the medicine from draining out. Follow your doctor's instructions about the use of cotton.


Do not place the dropper tip into your ear, or allow the tip to touch any surface. It may become contaminated.

Wipe the tip of the medicine bottle with a clean tissue. Do not wash the dropper tip.


Carbamide peroxide may be packaged with a bulb syringe that is used to flush out your ear with water.


When filling the bulb syringe, use only warm water that is body temperature (no warmer than 98 degrees F). Do not use hot or cold water.

Hold your head sideways with your ear over a sink or bowl.


Gently pull your ear lobe back and downward to open up the ear canal. Place the tip of the bulb syringe at the opening of your ear canal. Do not insert the tip into your ear.


Squeeze the bulb syringe gently to release the water into your ear. Do not squirt the water with any force into your ear, or you could damage your ear drum.


Remove the syringe and allow the water to drain from your ear into the sink or bowl.


Do not use carbamide peroxide for longer than 4 days in a row. Call your doctor if your ear symptoms do not improve after treatment, or if they get worse.

Clean the bulb syringe by filling it with plain water and emptying it several times. Do not use soap or other cleaning chemicals. Allow the syringe to air dry.


Store the medication and the bulb syringe at room temperature away from moisture, heat, and direct light.

What happens if I miss a dose?


Since carbamide peroxide is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of carbamide peroxide is not likely to cause life-threatening symptoms.


What should I avoid while using carbamide peroxide?


Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using this medication.


Carbamide peroxide side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using carbamide peroxide and call your doctor at once if you have a serious side effect such as:

  • dizziness;




  • ear pain, itching, or other irritation;




  • discharge or bleeding from the ear; or




  • decreased hearing for a prolonged period of time.



Less serious side effects may include:



  • temporary decrease in hearing after using the ear drops;




  • mild feeling of fullness in the ear; or




  • mild itching inside the ear.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect carbamide peroxide?


It is not likely that other drugs you take orally or inject will have an effect on carbamide peroxided otic. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Murine Ear Drops resources


  • Murine Ear Drops Side Effects (in more detail)
  • Murine Ear Drops Use in Pregnancy & Breastfeeding
  • Murine Ear Drops Support Group
  • 0 Reviews for Murine Ear - Add your own review/rating


Compare Murine Ear Drops with other medications


  • Ear Wax Impaction


Where can I get more information?


  • Your pharmacist can provide more information about carbamide peroxide.

See also: Murine Ear side effects (in more detail)


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